MSIS Annual Meeting Program

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Musculoskeletal Infection Society – North America
24th Annual Open Scientific Meeting
August 8 & 9, 2014 – Francis Drake Hotel, Charleston, SC Agenda

Friday – August 8, 2014

7:15 a.m.

Registration Open

7:15–8:00 a.m.

Continental Breakfast

8:00–8:05 a.m.

Welcome, Announcements, Disclosure – Camelia Marculescu, MD


Clinical Science Presentations Session 1 – Abinash Virk, MD, Moderator

8:06–8:12 a.m.

(18)F–FDG And (68)Ga–Citrate PET/CT Imaging May Mimic Periprosthetic Joint Infection (PJI) in Mom Patients with Moderate to Severe ARMD – Hannu T. Aro, MD

8:13–8:19 a.m.

Management of Psoas Muscle Abscess Associated with Skeletal
Infections – Maja Babic, MD

8:20–8:26 a.m.

Previous Periprosthetic Joint Infection Predicts Infection after New
Primary Arthroplasty – Gregory Deirmengian, MD

8:27–8:33 a.m.

Effectiveness of a Decolonization Program in Eradication of MRSA in
Patients Undergoing Elective Total Joint Arthroplasty
Bryan D. Springer, MD

8:34–8:40 a.m.

Outcome of Patients with Prosthetic Joint Infection, a Prospective Two Site Cohort Study: The Mayo Clinic, Rochester, MN and the Endo Klinik, Hamburg Germany – Elie F. Berbari, MD

8:41–8:51 a.m.


8:52–8:58 a.m.

Patients with Abnormal Infection Parameters need to be Investigated
Prior to Revision Arthroplasty – Speaker TBD

8:59–9:05 a.m.

Utility of Synovial White Cell Count and Neutrophil Differential during
Reimplantation Surgery – Corey Clyde, MD

9:06–9:12 a.m. Dual Antibiotic Prophylaxis is Associated with Acute Kidney Injury after Primary Joint Arthroplasty – P. Maxwell Courtney, MD
9:13–9:19 a.m.

Outcomes in TKA Complicated by Infection: A Matched Cohort
Design – Ivan Dzaja, MD

9:20–9:26 a.m.

Comparison of Gown Contamination in Simulated Total Joint Surgery
James Fraser, MD

9:27–9:33 a.m.

Gender Associated Disparities in Comorbidity: A Cause for PJI
Elie Ghanem, MD

9:34–9:44 a.m.


9:45–10:10 a.m.

Refreshment Break
Visit Corporate Partners, View Electronic Posters

10:11–10:17 a.m.

Minocycline–Induced Cutaneous Hyperpigmentation in an Orthopedic
Patient Population – Yuri Hanada, MD

10:18–10:24 a.m.        

Minocycline as Long Term Suppressive Therapy for Orthopedic
Infections – Yuri Hanada, MD

10:25–10:31 a.m.

Enhanced Detection of Staphylococcus aureus Colonization in Patients
Undergoing Total Joint Arthroplasty – Tyler White, BS

10:32–10:38 a.m.

Supra–Acetabular Cemented Roof Spacer to Improve Hip Stability in
1st Stage Infected THA – Surgical Technique and Results
Kevin Koo, MD

10:39–10:45 a.m.

The Results of Partial Retention, Limited Debridement, and Immediate Limited Exchange in the Treatment of Newly Infected Total Joints – Gerhard E. Maale, MD

10:46–10:56 a.m.



Basic Science Presentations Session 1 – Alex McLaren, MD, Moderator

10:57–11:03 a.m.

Locally Delivered Liposomal Amphotericin B Loaded Bone Cement is
Not Cytotoxic in Vivo – Josh Bingham, MD

11:04–11:10 a.m.

Organisms Causing PJI Stimulate Synovial Fluid Alpha–Defensin
Carl Deirmengian, MD

11:11 a.m.–11:17 p.m.

Gentamicin Elution from Prefabricated Articulating Spacers is Uniform among Sites – Oren Goltzer, MD

11:18–11:24 a.m.

Preliminary Results for Local Stimuli Responsive Drug Delivery Composite: Chitosan Sponge Augmented with Chitosan Microspheres Containing Fe3O4 Nanoparticles – Alex Hoban

11:15–11:21 a.m.

Functional Evaluation of Local Delivery of Amphotericin B and
Vancomycin from Modified for Biofilm Inhibition
Amber Jennings, PhD

11:22–11:28 p.m.

Novel Antibiotic–Loaded Point–of–Care Implant Coating Inhibits
Biofilm – Amber Jennings, PhD

11:29–11:39 p.m.


11:40 a.m.–12:30 p.m.

Symposium: Challenges in the Diagnosis and Management of Orthopedic Infections – Focus on the Immunocompromised Host Harry Demos, MD
Lee Leddy, MD
Douglas R. Osmon, MD

12:30–1:30 p.m. Luncheon


Basic Science Presentations Session 2 – Carl Deirmengian, MD, Moderator

1:35–1:41 p.m.

Extended Antibiotic Elution and Concomitant Bone Remodeling
by an Injectable Bone Graft Substitute Impregnated with Gentamicin
B. Fedrick Lindberg, MD

1:42–1:48 p.m.

Sonication Is Not Useful in Clinically Infected Trauma Explants
Nathaniel C. Wingert, MD

1:49–1:55 p.m.

Pre–Admission Chlorhexidine Preparation Reduces Surgical Site Infections Following Lower Extremity Total Joint Arthroplasty Michael A. Mont, MD

1:56–2:02 p.m.

The Effect of a Novel Marine Nuclease on the Removal of Biofilm: A New Approach to Periprosthetic Infection – Martin Marsh, MD

2:03–2:09 p.m.

Demonstration of the Ability of a CHG Incise Drape to Reduce Bacterial Contamination of Surgical Wounds in a Porcine Surgery Model – Linda Olson

2:10–2:20 p.m.


2:21–2:45 p.m.

Refreshment Break
Visit Corporate Partners, View Electronic Posters

2:46–2:52 p.m.

In Vivo Biofilm Infection Prevention using Local Drug Delivery via
Biocompatible Chitosan Paste – Cheyenne S. Rhodes, MD

2:53–2:59 p.m.

Liposomal Amphotericin B is Less Toxic than Amphotericin B Deoxycholate in Vitro – Justin Roberts, MD

3:00–3:06 p.m.

Premature Antibiotic Treatment can potentially Compromise the
Diagnosis of PJI – Ali Sina Shahi, MD

3:07–3:13 p.m.

Novel Therapeutic Approaches to Biofilm Associated Infection
Mark S. Smeltzer, MD

3:14–3:20 p.m.

Lower Bacterial Load with Prophylactic Regional Intraosseous Antibiotics in Murine Model of Total Knee Arthroplasty Timothy Roberts, MD

3:20–3:30 p.m.


3:31–4:45 p.m.

Symposium: Current Infectious Disease Concepts in
Musculoskeletal  Infections Abinash Virk, MD Cassandra Salgado, MD

4:45–5:00 p.m.

Announcements, Adjourn

6:00–8:00 p.m.

President’s Reception
Palmetto Garden Room and Courtyard
Belmond Charleston Place


Saturday – August 9, 2014

7:30 a.m.

Registration Opens

7:45–8:45 a.m.

Breakfast – Visit Corporate Partners, View Electronic Poster

8:00–8:30 a.m.

Business Meeting – MSIS Members Only

8:30–8:35 a.m.

Welcome, Announcements, Disclosure – Camelia Marculescu, MD

8:36–9:35 a.m.

Presidential Guest Lecture
State–of–the–art in Prosthetic Joint Infections: Current Concepts in
Diagnosis and Management
Dr. Werner Zimmerli


Clinical Science Presentations Session 2 – Steven Schmitt, MD, Moderator

9:36–9:42 a.m.

Comparison of the 2011 Musculoskeletal Infection Society (MSIS), the
2013 International Consensus Meeting (ICM) and the Infectious Diseases Society of America (IDSA) Diagnostic Criteria for Prosthetic Joint Infection (PJI) – Dante P. Melendez Lecca, MB, ChB

9:43–9:49 a.m.

The Economic Impact of Periprosthetic Infections Following Total Hip
Arthroplasty at a Specialized Tertiary–Care Center
Michael A. Mont, MD

9:50–9:56 a.m.

Periprosthetic Shoulder Infection in the United States: Incidence and

Economic Burden – Surena Namdari, MD

9:57–10:03 a.m.

A Functional Antibiotic Spacer Provides Patients with Similarly Satisfying Options of One or Two Stage Treatment for Chronic Periprosthetic Infection – Dr. Aidin Eslam Pour

10:04–10:10 a.m.

The Limited Utility of Nucleated Cell Counts for the Diagnosis of
Infection in the Setting of Periprosthetic Fracture
Stephen Preston, MD

10:10–10:20 a.m.


10:20–10:45 a.m.

Refreshment Break
Visit Corporate Partners, View Electronic Posters

10:46–10:52 a.m.

Complications in Underweight Total Knee Arthroplasty Patients
Antonia Chen, MD

10:53–10:59 a.m.

Delaying Reimplantation Following Resection Arthroplasty Does Not Improve Outcomes: A Report from Two High Volume Orthopaedic Centers – Anthony Tokarski, MD

11:00–11:06 a.m.

Mid–Term Survivorship and Outcomes of Two–Stage Revisions for
Infected Total Hip Arthroplasty – Edward Vasarhelyi, MD

11:07–11:13 a.m.

A New National Surgical Site Infection Improvement Program for New
Zealand: Project and Results – Kelly Vince, MD

11:14–11:24 a.m.


11:25–11:31 a.m.

Prosthetic Joint Infection due to Salmonella Species: A Case Series
Abinash Virk, MD

11:32–11:38 a.m.

Method of Tissue Sampling may have an Effect on Contamination Risk
Antonia Chen, MD

11:39–11:45 a.m.

Surgical Case Order in Total Joint Arthroplasty has No Effect on
Infection Risk – Antonia Chen, MD

11:46–11:52 a.m.

The Incidence of Periprosthetic Joint Infection after Aseptic Index
Knee Revision Surgery – Paul McLendon, MD

11:53 a.m.–12:05 p.m.


12:05–12:15 p.m.

Announcements, Adjourn